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What’s New in Mitochondria
A severe impairment of cognitive function characterizes dementia. Mild cognitive impairment represents a transition between normal cognition and dementia. The frequency of cognitive changes is higher in women than in men. Based on this…
White matter degeneration is a pathological hallmark of neurodegenerative diseases including Alzheimer’s. Age remains the greatest risk factor for Alzheimer’s and the prevalence of age-related late onset Alzheimer’s is greatest in females. We investigated…
Estrogen-mediated regulation of the bioenergetic system: estrogen signalling supports and sustains glucose metabolism in the brain by regulating expression of glucose transporters, which results in increased glucose uptake, and by stimulating glucose metabolism, mitochondrial…
In the absence of estradiol, brain glucose transport diminishes significantly. This effectively starves the brain for energy inducing severe bioenergetic deficiencies with all of the concordant neuronal damage one might expect. The reduction in…
Estradiol and its receptors are key players in the physiology and insulin production capacity of the β cells of pancreatic islets. Estradiol administration is associated with pancreatic islet hypertrophy and increased insulin release from…
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Sandra Ishkanes
Functional Medicine Practitioner
BSc MA DipION
sandra@gynelogic.co.uk
Brighton, UK
Functional Medicine Practitioner
BSc MA DipION
sandra@gynelogic.co.uk
Brighton, UK
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