Journal

Primary Research

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    Using Copper to Improve the Well-Being of the Skin

    Copper has two key properties that are being exploited in consumer and medical device products in the last decade. On the one hand, copper has potent biocidal properties. On the other hand, copper is…

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    Impacts of Psychological Stress on Osteoporosis: Clinical Implications and Treatment Interactions

    While osteoporosis and psychological stress occur via differing mechanisms, there are several potential molecular links that exist between a pathological response to stress and the development of bone disease. Although not a comprehensive list,…

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    Role of cortisol in the pathogenesis of postmenopausal osteoporosis: relationship to bone structure

    Excess glucocorticoids are well recognised as a cause of osteoporosis; they inhibit osteoblast function and increase osteoblast and osteocyte apoptosis resulting in thinning of the trabeculae. The circadian rhythm of bone turnover, which is…

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    Stress Factors Increase Osteoporosis: A ComparativeAssessment of Osteocalcin and Cortisol Levels in Menopausal Women

    Osteoporosis, a consequence of menopause in the biological cycle of women, emerges with the conclusion of reproductive capabi lities.Hormonal changes during this phase contribute to the development of the disease. The study evaluated the…

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    Association of Menopausal Vasomotor Symptoms With Increased Bone Turnover During the Menopausal Transition

    The purpose of this study was to determine the longitudinal association between menopausal vasomotor symptoms (VMS) and urinary N-telopeptide level (NTX) according to menopausal stage. We conclude that among early perimenopausal and late perimenopausal women,…

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    Presence of vasomotor symptoms is associated with lower bone mineral density

    Objective: To determine whether women with vasomotor symptoms (VMS) have lower bone mineral density (BMD) than women without VMS. Design We analyzed data from baseline to annual follow-up visit 5 for 2213 participants in…

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    Endocrinal metabolic regulation on the skeletal system in post-menopausal women

    Loss of estrogen results in reduced osteoblast mediated bone formation and enhanced osteoclastic resorption (Emmanuelle et al., 2021). Given the recent expansion of interest in understanding how these cellular processes are regulated via metabolic flux and…

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    Osteocalcin, a promising marker of osteoporosis: evaluation in post-menopausal females with osteoporosis

    Background: Osteocalcin, has high affinity for calcium. In osteoporotic women, deficiency of calcium may lead to lowering of the formation of hydroxyapatite crystals. Thus, in the state of hypo mineralization, free osteocalcin available in the…

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    Menopause and cognitive impairment: A narrative review of current knowledge

    A severe impairment of cognitive function characterizes dementia. Mild cognitive impairment represents a transition between normal cognition and dementia. The frequency of cognitive changes is higher in women than in men. Based on this…

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    Effects of ketone bodies in Alzheimer’s disease in relation to neural hypometabolism, β-amyloid toxicity, and astrocyte function

    Brain hypometabolism precedes clinical signs ofAlzheimer’s disease: Frackowiak et al. (1981) found a decline in cerebral bloodflow and mean cerebral oxygen utilization, i.e., hypometabolism, which is correlated with the severity of dementia. Global oxygen…

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Sandra Ishkanes
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Brighton, UK

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